CFID works with strategic partners and supporters to hasten
the discovery of innovative solutions to better understand,
diagnose, prevent, control and treat existing and
emerging infectious diseases that threaten our good health.

Research in Action

Samples of current research carried out by CFID-funded investigators and trainees are showcased below.


2017 Dr. Juan A. Embil Award for Infectious Disease Research

Cheng MP, Chakra CNA, Yansouni CP et al. Risk of Active Tuberculosis in Patients With Cancer: A Systematic Review and Meta-analysis. Clinical Infectious Diseases. 2017;64(5):635-644

  • Trainee - Dr. Matthew P. Cheng, Division of Infectious Diseases and Department of Microbiology and Immunology, McGill University Health Centre, Montreal, PQ
  • Supervisor - Dr. Christina Greenway, Division of Infectious Diseases, Jewish General Hospital and McGill University. Montreal, PQ

Download winning publication


2017 CFID Safe Drinking Water Pilot Project

Naturized E. coli and fecal indicators in drinking water wells: implications for testing, risk assessment and as potential environmental reservoirs for antimicrobial resistance

Dr. Anna Majury, PhD, DVM, Department of Biomedical and Molecular Sciences, Division of Microbiology and Immunology and Schools of Environmental Sciences and of Public Health Sciences, Queen's University at Kingston, and Regional Microbiologist, Public Health Ontario

Read project synopsis


2017 Summer Medical Student Research Projects

Molecular Epidemiology of Mycobacterium tuberculosis in Newfoundland and Labrador

  • Student - Lucy Smith, Med II, Memorial University School of Medicine, St. John's, NF
  • Supervisor - Dr. Peter Daley MD, Assistant Professor, Infectious Diseases & Medical Microbiology, Faculty of Medicine, Memorial University, St. John's, NF
Read project synopsis


Exploring the Live Birth Rates of Women Living with HIV in British Columbia and the CARMA (CIHR Emerging Team Grant on HIV Therapy and Aging) Cohort

  • Student - Clara van Ommen, Med II, University of British Columbia School of Medicine, Vancouver, BC
  • Supervisor - Dr. Melanie Murray MD/PhD, Assistant Professor, Division of Infectious Diseases, University of British Columbia, BC Women's Hospital and St. Paul's Hospital, Vancouver, BC
Read project synopsis


2017 Summer Undergraduate Student Research Project

Whole Genome Sequencing of Mumps Virus from an Adult Outbreak in Brisith Columbia

  • Student - Thenuga Sasitharan, Year 4, Medical Laboratory Science, University of British Columbia, Vancouver, BC
  • Supervisor - Dr. Agatha Jassem PhD, Clinical Assistant Professor, Department of Pathology & Laboratory Medicine, University of British Columbia and BCCDC Public Health Laboratory
Read project synopsis


2016 Dr. Juan A. Embil Award for Infectious Disease Research

McKay R, Mah A, Law M, McGrail K, Patrick DM. 2016. Systematic review of factors associated with antibiotic prescribing for respiratory tract infections. Antimicrob. Agents Chemother. doi:10.1128/AAC.00209-16, published online May 2, 2016.

  • Trainee - Dr. Allison Mah, University of British Columbia
  • Supervisors - Dr. David M. Patrick, University of British Columbia

Download winning publication


2016 Summer Medical Student Research Projects

Tan C, Vermeulen M, Wang X et al. Variability in antibiotic use across Ontario acute care hospitals. J Antimicrob Chemother. 2017;72(2):554-563

  • Student - Charlie Tan, Med III, Michael G. DeGroote School of Medicine, McMaster University
  • Supervisor - Dr. Nick Daneman MD, MSc, FRCPC, Sunnybrook Health Sciences Centre, University of Toronto
Download publication


Biomarkers of inflammation and endothelial activation in vertically HIV-1 infected children

  • Student - Jeremy Soo, Med I, University of Alberta School of Medicine
  • Supervisor - Dr. Michael Hawkes MD, PhD, FRCPC, Department of Pediatrics, University of Alberta
Read project final summary


2016 Summer Undergraduate Student Research Project

Understanding poor vaccine responses: transcriptomics of vaccine failure

  • Student - Kathleen Miller, Year 3, Microbiology & Immunology, Dalhousie University
  • Supervisor - Dr. Lisa Barrett, MD, PhD, FRCPC, Department of Microbiology & Immunology, QE II Health Sciences Centre, Dalhousie University
Read project final summary


2015 CFID Themed Special Pilot Project

Performance and cost-effectiveness evaluation of multiplex molecular testing for enteric pathogens in a Canadian health-care setting

Dr. Astrid Petrich, Division of Microbiology, The Hospital for Sick Children and University of Toronto

Read project synopsis


2015 CFID Safe Drinking Water Pilot Project

Metagenomic analysis of drinking well water for rural and marginalized populations in regional Ontario - implications for testing, including human, public and environmental health

Dr. Anna Majury, PhD, DVM, Department of Biomedical and Molecular Sciences, Division of Microbiology and Immunology and Schools of Environmental Sciences and of Public Health Sciences, Queen's University at Kingston, and Regional Microbiologist, Public Health Ontario

Read project final summary


2015 Dr. Juan A. Embil Award for Infectious Disease Research

MacFadden DR, Ridgway JP, Robicsek A, Elligsen M, Daneman N. 2014. Predictive utility of prior positive urine cultures. Clin Infect Dis. 59(9):1265-71.

  • Trainee - Dr. Darren R. MacFadden, University of Toronto
  • Supervisors - Dr. Nick Daneman, University of Toronto
Download winning publication


2015 Summer Medical Student Research Project

Community-acquired Clostridium difficile infections

  • Student - Christina Thornton, Med 2, MD/PhD Program, University of Calgary
  • Supervisor - Dr. Dylan R. Pillai, Medical Microbiologist, Calgary Lab Services, Division of Infectious Diseases, Department of Microbiology & Infectious Diseases, University of Calgary
Read project final summary


2015 Summer Undergraduate Student Research Projects

Designing and testing the efficacy of a RSV phosphoprotein mimetic on the inhibition of RSV replication and infection

  • Student - Christopher Chiang, Honours Life Science Program, McMaster University
  • Supervisor - Dr. James Mahony, St Joseph Hospital, McMaster University
Read project final summary


Parasitologic correlates of genomic differences in Plasmodium ovale wallikeri and Plasmodium ovale curtisi

  • Student - Melissa Phuong, Honours Bachelor Health Sciences Program, McMaster University
  • Supervisor - Dr. Andrea K. Boggild, University of Toronto
Read project synopsis


2014 CFID Safe Drinking Water Pilot Project

Electrochemical disinfection using copper and/or silver

Dr. Younggy Kim PhD, Department of Civil Engineering, McMaster University, Hamilton, ON

Read project synopsis


2014 Dr. Juan A. Embil Award for Infectious Disease Research

Leis JA et al. Reducing antimicrobial therapy for asymptomatic bacteriuria among noncatheterized inpatients: A proof-of-concept study. CID 2014 Feb 26 [Epub ahead of print].

  • Trainee - Dr. Jerome A. Leis, University of Toronto
  • Supervisors - Dr. Allison McGeer and Dr. Wayne L. Gold, University of Toronto
Download winning publication


2014 Summer Student Research Projects

Pandemic waves-mortality in the Canadian expeditionary forces, 1918

  • Student - Alex Rewegan, McMaster University (Anthropology)
  • Supervisor - Ann Herring PhD, Department of Anthropology, Faculty of Social Sciences, McMaster University
Read project final summary


The prevalence of STEC and stx+ wells and microbial source tracking of faecal contamination in rural Southern Ontario drinking water wells

  • Student - Sophie Felleiter, Queen's University (Life Sciences)
  • Supervisor - Anna Majury PhD, PHO, and Gerald Evans MD, Department of Medicine, Queen's University
Read project final summary


The role of Pseudomonas aeruginosa and and the lung microbiome in Pseudomonas eradication in cystic fibrosis

  • Student - Lauren Smith, McMaster University (Honours Integrated Science Program)
  • Supervisor - Valerie Waters MD, Hospital for Sick Children, University of Toronto
Read project final summary


2013 Dr. Juan A. Embil Award for Infectious Disease Research

Asadi L et al. Macrolide-based regimens and mortality in hospitalized patients with community acquired pneumonia: A systematic review and meta-analysis. ClD 2012;55:371-380.

  • Trainee - Dr. Leyla Asadi, University of Alberta
  • Supervisors - Drs. Sumit Majumdar and Thomas Marrie
Download winning publication


2013 Summer Student Research Projects

Exploring the overexpression of a central regulator of Aspergillus fumigatus asexual sporulation, brlA, as a way to reduce virulence through reduced vegetative growth

  • Student - Mohamad Rabbani, McGill University (Bachelors Program)
  • Supervisor - Don Sheppard MD, Department of Microbiology & Immunology, McGill University
Read project report


A Listeria monocytogenes-based Vaccine for Respiratory Syncytial Virus

  • Student - Zach Liang, Developmental Biology, Faculty of Science, University of British Columbia (Bachelors Program)
  • Supervisor - Tobias Kollman MD, PHD, Division of Infectious and Immunological Diseases, Department of Pediatrics, Child and Family Research Institute; BC Children’s Hospital
Read abbreviated project report


Predictors of Influenza vaccine failure and impact of influenza immunization on severity of illness and outcomes among hospitalized Canadian adults

  • Student - Tara Riddell, Dalhousie University (MD Program)
  • Supervisor - Shelly McNeil MD, Canadian Center for Vaccinology, IWK Health Centre, Halifax, Nova Scotia
Read abbreviated project report


2012 CFID Safe Drinking Water Pilot Project

Association of enteric viruses in source water for drinking (surface and ground water) and sporadic viral gastroenteritis and outbreaks in Alberta

Dr. Bonita E. Lee MD, Division of Infectious Disease, Dept. Pediatrics, University of Alberta, Edmonton, AB

Read project synopsis


2012 Dr. Juan A. Embil Award for Infectious Disease Research

Costiniuk CT et al. Circulating endothelial progenitor cell levels are not reduced in HIV-infected men. J Infect Dis 2012;205:713-717

  • Trainee - Dr. Cecilia T. Costiniuk
  • Supervisor - Dr. Jonathan B. Angel, Division of Infectious Diseases, Ottawa Hospital - General Campus
Download winning publication

2012 Summer Student Research Projects

Conventional compared to biofilm antimicrobial susceptibility testing for Stenotrophomonas maltophilia isolates from cystic fibrosis patients (submitted for publication).

  • Student - Kitty Wu (Cells Systems Biology, University of Toronto)
  • Supervisor - Dr. Valerie Waters, Pediatric Infectious Diseases, Hospital for Sick Children
-- Accepted for publication in Antimicrobial Agents Chemotherapy, January 2, 2013 Read project abstract


Deficits in cell-mediated immune recovery among HIV+ individuals on effective antiretroviral therapy

  • Student - Parmvir Parmar (Biochemistry, Microbiology and Immunology, University of Ottawa)
  • Supervisor - Dr. Jonathan B. Angel, Division of Infectious Diseases, Ottawa Hospital-General Campus
Read abbreviated project report


Invasive Streptococcus pneumoniae in Canada 2012: Serotyping, antimicrobial susceptibility and virulence assessment

  • Student - Alyssa Golden (Molecular Biotechnology (Honours), University of Manitoba)
  • Supervisor - Dr. George Zhanel, Department of Clinical Microbiology, Health Sciences Centre
Read abbreviated project report


 

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